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Hemochromatosis (HE-mo-kro-ma-TOE-sis) is a disease in which too much iron builds up in your body Hereditary Hemochromatosis is the most common genetic disorder of persons of northern European extraction. Most people with hemochromatosis inherit the condition from their parents. If you inherit two hemochromatosis genes, one from each parent, you will have the condition. These two abnormal genes cause your body to absorb more iron than usual from the diet. The most common gene involved in causing Hereditary Hemochromatosis is the HFE gene. One in seven persons of northern European extraction carries one copy of the mutant HFE gene C282Y. Approximately 1 in 200 to 300 persons of northern European extraction carry two copies of C282Y. In some northern European populations e.g. Ireland, Iceland and Brittany the percentage of persons carrying one copy of C282Y is higher. Predictably countries settled by northern Europeans e.g. Australia, South Africa and Canada have high rates of Hereditary Hemochromatosis. Two copies can predispose to the iron overload disorder hemochromatosis. This may present as chronic fatigue, skin pigmentation, heart irregularities, impotence, diabetes, dysfunction of the liver, cirrhosis or cancer, premature menopause, arthritis or decreased functioning of the thyroid. Even one copy of C282Y can be associated with too much iron in the liver, high cholesterol, diabetes and the skin disorder porphyria cutanea tarda. Other mutant genes exist and are distributed throughout the world's population. Effects of Hemochromatosis In hemochromatosis, iron can build up in most of your body’s organs, but especially in the liver, heart, and pancreas. When this happens, the iron can poison the organs and lead to organ failure. If Hereditary Hemochromatosis is not treated liver disease may be fatal. Hemochromatosis can lead to enlargement, cirrhosis or cancer of the liver. Heart Problems. Hemochromatosis can cause irregular heart rate or rhythm and lead to heart failure Pancreas. Hemochromatosis can lead to diabetes mellitus. Patient Outlook The morbidity and mortality of Hereditary Hemochromatosis can be reduced by early diagnosis and treatment by phlebotomy or blood letting. Bloodletting or deironing often results in considerable improvement in the health of patients who suffer from Hereditary Hemochromatosis. Early diagnosis and treatment are important. Treatment may be able to prevent, delay, or sometimes reverse complications of the disease Diet can help. When the diagnosis of hemochromatosis is made it is important to adjust the diet so that too much iron is not being absorbed because of an improper diet. The biggest considerations are not to take medications which contain iron, consume too much alcohol or Vitamin C. Excessive alcohol consumption has shown to greatly increase iron absorption in those with hemochromatosis Vitamin C enhances the absorption of iron. It is wise only to consume a moderate amount and not take Vitamin C tablets. Vitamin C has been known to precipitate heart palpitations in those with hemochromatosis. Treatment of iron overload disorder hemochromatosis is critical in order to prevent damage to vital organs and serious complications such as diabetes and cirrhosis of the liver. For people who are diagnosed and treated early, normal life spans are possible. If left untreated, hemochromatosis can lead to severe organ damage and even death. penis girth enlarement vimax free penis enlargement cheapest penis elargement pills free penis enargement pro solution review top penis enlargment pills penis elargement cream compare penis enlarement pills

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Sexual dissatisfaction makes a man to fall prey to bitterness in life. A man is not fully happy until his sexual intimacy is aimed to make his wife physically content. Among various health problems in men, impotence or Erectile Dysfunction (ED) is foremost in being a big talk of the day today. Levitra is one of the most popular drugs today to help men suffering from impotence. Levitra is a very effective power booster which enables men to retain his erection for long, and helps people suffering from ED in a great way. There are many reasons such as smoking, drug or alcohol abuse, particularly over a long period of time which degenerate the blood vessels of the penis, and cause impotence or ED. Levitra works by reducing the effects of an enzyme called PDE-5. Reduced activity of PDE5 enzymes causes more blood flow to the penis. Increased blood flow to penis results in an improved and longer erection. Levitra medication drug has to be taken according to doctor’s instructions. Doctor normally recommended 10 mg of starting dose for most men. Levitra should be taken approx 1 hour prior to sexual activity. It starts working just within 16 minutes of its intake and may last for up to 24 hours. One must be aware of the fact that Levitra alone can’t give an erection. One needs sexual stimulation for an erection to happen, and get his erection improved through Levitra. this drug is not an aphrodisiac or hormone, and nor does it cure Erectile Dysfunction. It improves the hardness of one’s erection as well as ability to maintain erection during sex. The most common side effects of taking Levitra are headaches, flushing, stuffy or running nose. Doctor’s advice is inevitable, if any serious abnormalities are seen during its usage. The tremendous success of Levitra medication in helping men suffering from impotence or ED has made this drug a very popular among male of all ages. penis elargement secret medical penile enlargment penis enlargement stretcher cheap penis enlargment pills penis enlargement excercises homemade penis elargement free penis enhancement enargement forum free matter penis size manual penis enargement exercise

There is no doubt that jewelry is one of the passions of both men and women. The purchase of jewelry increases each year both from the local jewelry shops and online shops. Several customers search for the ideal necklace, pair of earrings, bracelet, or ring from various stores. Who would not think about how wonderful pieces of adornment jewelry can be? They are treasured possessions. They are truly fascinating. And the jewelers who make them can be quite talented. Who Is a Jeweler? A jeweler is one who works on crafting valuable stones. He cuts the stones into appropriate pieces, sets them according to the right size and designs, and likewise polishes them so they will be nice to hold and dazzling to look at. A jeweler also makes or designs jewelry according to the plan he has devised. Or, he may pattern his craft according to the designs provided by certain designers or the designs that are clearly specified by the customers. In addition to creating several variations of jewelry, a jeweler is also skilled in repair work. Hence, a jeweler is a genius in both the enlargement and reduction of the sizes of the rings, restoring kaput mountings and clasps, resetting or altering the positions of the gemstones, engraving, and polishing. How Does a Jeweler Complete His Work? Once the jeweler has conceptualized the design he wishes for a piece of jewelry, the first thing he does is carve the wax that will serve as the model when he begins to cast the metal. Next, each of the parts is soldered as one, after which, the jeweler may either decide to mount any gemstone or whittle any suitable design to the metal itself. The final step of polishing the jewelry to perfection follows. Jewelers utilize different tools to complete their work. With the aid of the continuing advancement of technology, jewelry-making has become easier and more affordable, and it yields pieces of the finest quality. pennis enlargement excersizes penile enlargement system penis enlargement pills top pnis enlargement pills penis enlagement excercises penis enargement surgeries penile enlargment drug free penis elargement tip manual penis enargement exercise

1. Planning Renovations Any project will be more successful, given well-defined goals. In every household project, the following three points can be applied: FORM: What do you want it to look like? FUNCTION: What do you want it to do for you? COMPATIBILITY: What factors exist that might limit what you can do, and will the finished product look good on your house? Once you've completed this part of your homework, it's time to decide if you'll built it yourself, hire a contractor, or be your own contractor and perhaps sub-contract some of the work. Sub-contracting may sometimes seem to over-complicate things and even look wasteful, but just remember - some jobs can look deceivingly simple until you actual get into the nitty-gritty of them. A general contractor's job is to co-ordinate and orchestrate the whole schmozzle to completion. 2. Finding A Contractor My card...The process of finding a good contractor is essentially the same, whether you decide to hire a general contractor, or one or more sub-contractors. The best reference for a contractor is word of mouth from a satisfied client. If you don't know anyone who has had renovations or repairs done in the area you need, look for work trucks or signs in your neighborhood. Knock on doors, and ask the homeowners if they are satisfied with the work being done. Once you contact a contractor, ask for references, and follow through by calling their previous clients with a set of questions that will give you the information you are looking for. The following are samples of questions that could be asked of any reference: 1. Did the job come in at the quoted price? 2. Did the job come in on time? 3. Was the work site left clean each day? 4. Was the quality of the workmanship satisfactory? 5. Was the quality of the materials used satisfactory? It is always recommended that you talk to more than one company, so that you have a basis for comparison. Listen to their technical information, and note their customer relation skills. If the contractor doesn't do a very good job of communicating with you before you hire him or her, there may be a higher likelihood of miscommunications during the work. Sometimes the best companies will be very busy and you will have to wait for their services. Other times, good companies may have time slots between large projects that smaller jobs can fit into. Ask what the company's schedule has been like for the past 6 months to a year. Reputable companies are usually busy all year round in any economic situation. 3. The Estimate, or Quote Meeting the Contractors Remember that the contractor you choose could be spending a lot of time in your home, so look for someone you feel at ease with. You should meet individually with each potential contractor. Be prepared to discuss products and designs; know what you want and how much you can spend. Take note if the contractors are on time, if they listen and answer questions, willingly give information about their company and their customers; and if they seem to have any aversion to your ideas. The Estimate This is where you'll likely make your choice of contractor. Each potential contractor will present a proposal, including design and cost information. Review the estimates, ensuring that they accurately relfect your wishes, and make comments and/or any changes that are required. How Are Jobs Estimated? Work that involves structural changes to the home, custom designs, or enlargement of some of the mechanical systems is typically quoted by the job. It can be very difficult for a contractor to know exactly how much time an intricate custom job will take, particulary if a number of trades are required, and the different parts of the job are interdependent. Get it in writing!Simpler, straightforward jobs are often quoted by the square foot. Examples are laying sod, painting, roofing, drywall or refinishing floors. The quoted price will typically be set to include everything (ie. labour, materials, travel, etc.). Smaller jobs may also be quoted buy the hour, and if the job is fairly routine, such as installing addtional electrical outlets or drywalling, the figures are typically in line. In this situation you will pay the tradesperson for time, plus the cost of the materials used in the project. The Final Design and Quote If you have a contractor with good references and the estimate looks good, you now need to get a firm quote, including final designs. The design should include detailed specifications for the work and the materials to be used. (Another option is to have an architect or designer produce the plans and ask the contractors to bid on the job, based on these plans.) Make sure the final specs are accurate and reflect your wishes, and make your final comments and changes. After you accept the final quote, the cost of further changes will likely be added to the job. Ask how long the stages of the work will take, so that you can monitor progress. 4. The Paperwork Cash is King, however... ... take care, lest the cash deal of the century turn into the mistake of a lifetime! One reason for cash payment is the avoidance of paperwork and taxes. Taxes and other legalities aside, the absence of contracts and permits can be extremely risky. Ooh, I love to save money!Cash contractors often don't pay Workers' Compensation fees, and you could be held legally responsible for any worker injured on your property. If the contractor gives you the product warranty cards, you'll be covered for defective materials provided they were properly installed, but don't expect good follow-up service on a cash deal. You would also have difficulty supporting any legal actions without any paperwork. The overall quality of a project may be compromised in the absence of paperwork, and cash paid in advance (rather than by cheque) will be all but impossible to retrieve if things go sour. Building, plumbing and electrical codes may require that all or parts of your project be performed by licensed tradespeople, and sometimes licenses are required to obtain the permits. If the tradespeople aren't licensed, the contractor probably isn't insured. And if your contractor isn't insured, then depending on the nature of the job, neither is your house while he works on it. The Contract Agreements in writing are less vulnerable to miscommunications, than are verbal ones, and far easier to enforce. Some of the points included in a good contract are: 1. Full job description, including all aspects of the work; demolition, renovation, reconstruction and finishing. 2. Material specifications, including type, model, number, color, and size where applicable, and who's supplying what. 3. Start and finish dates. 4. Payment schedule; 40/40/20 is generally acceptable. 5. Permits, and who's responsible for obtaining them. 6. Clean-up and trash removal. 7. On site behaviour. 8. Change order clause: Have any changes to the original job specifications in writing with a requirement that you "sign off" any change before the work is performed. 9. Arbitration: Aree how disagreements will be handled before the work begins. 10. Contractor's insurer and policy number. 5. The Work MORE POWER! Problem Avoidance: If you've carefully chosen your contractor, and made adequate preparations (including making the site ready for the trades people and workers), this part should be easy! The actual work should closely follow what was written into the contract, however you still need to monitor the ongoing project, and in some cases you'll be required to make additional decisions. There are often unforseen difficulties, or you may simply wish to ask for changes as the work proceeds. Site Preparation: Remove furniture and stored articles from the work area, and cover carpets and other items that may not be moveable. It is in your own best interest to make arrangements for storage, clean-up and refuse areas convenient to the work area. Project Coordination: Effective communication is the greatest secret to successfully completing any project. Maintain regular contact with your contractor(s) so that the unexpected can be dealt with expediently. Hidden Conditions: A thorough inspection performed in conjuction with estimation should preclude any major changes, however there are structural and mechanical conditions initially hidden from view, which even the most experienced renovator may not be able to predict. Be prepared to negotiate changes for "hidden conditions". What to do if a problem develops: 1. Bring all problems, perceived and real, to the attention of your contractor(s). 2. Is it major or minor? If minor, and the contractor is present at the time, discuss it and negotiate a resolution. If it's minor, and/or looks like it can wait, start a list of minor observations that you can bring to his or her attention when appropriate. 3. Major problems should be dealt with immediately. If your contractor is not present at the time, make every effort to contact him or her as soon as possible. This may avert furtherance of the problem. 4. Given that your contractor responds satisfactorily, carry on. If not, try again and if necessary, write a letter. If you still don't get satisfaction, look to a third party such as the Ontario Renovators Council or the Ontario Home Builders Association. These agencies should be approached only if you are certain that a resolution cannot be achieved with the contractor. Legal counsel should be an absolute last resort. There's no use making a mountain out of a molehill, and thereby delaying succesful completion of the project. THE BOTTOM LINE: careful contractor selection + a good contract = successful job penis enlarement testimonials herbal natural penis enlargement herbal pnis enlargement penile enlargement excercises vimax penis girth enlargement pennis enlargement exercise does penis elargement work free pennis enlargement manual penis enargement exercise

There are three different types of muscle tissue in the human body: cardiac muscle, which is only in the heart; smooth muscle, which is found in organs & blood vessels; and of course skeletal muscle, which is found all over the body and is responsible for movement. All three of these muscle types have distinctly different anatomical structure and function in the body. We know that muscles get bigger and stronger when put under stress, which is called adaption. Which simply means that the muscle is preparing itself in case it’s put under the same type of stress again. An analogy is calluses on your hand, if you rub your hand on a course surface causing enough friction eventually the skin adapts by building up calluses, thus protecting it self from future happenings. Muscle reacts much the same way, if you train them or put them under enough stress they will adapt to this stress by growing bigger and stronger. So the next time you train them they will be capable of handling this new level of stress. Now obviously that is a very basic explanation, but hang on to your dumbbells we’ll get more in depth! Inside a muscle there are groups of motor units separated by membranes. Each motor unit consists of a single neuron and all of the muscle fibers it stimulates. In muscles such as the hand where fine motor control is necessary the ratio of nerves to fibers will be much higher than that of a muscle such as the calf. Muscle fiber consists of myofibrils, a myofibril is a small bundle of myofilaments. Myofilaments are mainly comprised of two types of proteins called actin and myosin. The myofilament is the part of the muscle that actually shortens upon contraction where the actin and myosin filaments slide over each other, which is called the sliding filament theory. Basically by the way of chemical bonds and receptor sites located on the myofilaments the actin and myosin attract each other thereby causing a contraction. A contraction can be held until fatigue sets in, and the strength of a contraction is determined by the number of motor units that are recruited. Inevitably, the more force that is necessary for muscle contraction requires an increased number of motor units to allow the muscle to contract. Within skeletal muscle there are three types of muscle fibers: Type I, Type IIa and Type IIb. Everyone has their own unique distribution of these fibers, some people are predominately Type I, and some Type IIa, however the “average person” has an even amount of red and white fiber. Type I muscle fiber often referred to as slow-twitch or red fiber and is highly resistant to fatigue and has a high oxidative capacity, This muscle fiber is responsible for aerobic exercises and activities, such as running. Type IIa muscle fiber often referred to as fast-twitch or white fiber is an intermediate fiber and they’re larger in size and much stronger than Type I fibers. Type IIb muscle fiber, which are also fast twitch & white fiber, are capable of producing more force than Type IIa, but they’re low in oxidative capacity, and fatigue very quickly. Fast twitch fibers have thicker nerves that give them an increased contractile impulse, which is measured by the number of twitches per second, hence the name fast twitch fiber. Slow twitch fibers have smaller nerves, thereby twitch much slower, however they have a higher number of mitochondria, which increases their oxidative capacity. Mitochondria are the cells in a muscle that synthesize ATP (Adenosine Triphosphate), often referred to as the cell’s “powerhouse”. Okay, so now you have a basic understanding of muscle physiology, let’s talk about how we make them grow! The enlargement of a muscle fiber is called hypertrophy. As I mentioned earlier muscle growth or hypertrophy is a result of adaption to a new stress placed upon the muscle. So, what is the best form of stress? Well, there really is no single best principle that will work for every person. This is where the muscle fiber type distribution that you posses becomes important. If you train using appropriate methods based on your individual body type you will ultimately get faster results. First I would like to define the 7 Laws (adapted from the writings of Fredrick C. Hatfield) that should be adhered to regardless of the type of training system you employ: Law I – The Principle Of Individual Differences We must recognize and accept that we are all different based on genetics. We all have different body types, often referred to as the somatotypes: ectomorph, mesomorph & endomorph (most people are a combination of all 3 body types). The somatotypes is a very general classification that can help you determine the best type of training for you, but it’s a very basic tool and there is much more involved in one’s genetic make-up and musculature. Somatotypes are defined as follows: - Ectomorph: Thin, light bone structure, difficult to gain mass. - Mesomorph: Muscular, lean, gains muscle mass relatively easy. - Endomorph: Heavy, large bone structure, propensity to weight gain. Law II – The Overcompensation Principle The body overcompensates in defense to the stress placed upon it. A muscle grows bigger and stronger when trained with heavy weights, just as your hand will develop calluses when friction is applied. If you do not change the form of stress the muscles will have no reason to further adapt. Law III – The Overload Principle Relates to Law II, in that to gain further size & strength, endurance, etc., you must use training that is greater than what the body would normally encounter. If you train with the same amount of weight and/or repetitions every workout your muscles will not continue to adapt. Thus, you must overload in some way to cause further adaption. Law IV – The SAID Principle Specific Adaption to Imposed Demands, basically this law states that in order to meet your training objectives, e.g. increase explosiveness, you must you use specific training methods that will increase explosiveness. Or, if your goal is to increase limit strength, you must train with heavy weights. Law V – The Use/Disuse Principle Very simply put: “use it, or lose it”! If you increase a muscle via weight training you must continue to place the same or more stress upon the muscle or it will inevitably return to it’s normal size, which is called atrophy. Law VI – The Specificity Principle This law states that you must progress from foundational training to specific training to meet your final objective, whether it be a competition or improving your game of golf. An example would be to increase your maximum squat you need to use squats in your training rather than leg presses. Law VII – The GAS Principle General Adaption Syndrome, there are three stages: the alarm stage (intense training), the resistance stage (adaption) and the exhaustion stage (over training). If one is not careful in their training regimen they will over train according to this law. To avoid over training you must use periods of high intensity training, followed by periods of low intensity training and/or rest. So, no matter what method of training you utilize, the 7 Laws should be adhered to as closely as possible to facilitate maximum gains and to avoid a state of over training. The two most common questions are how much weight and how many reps? Unfortunately there is no magic number; it will vary from individual to individual. An “ectomorph” who is predominantly red fiber will respond better to higher repetition training, whereas a “mesomorph” who is predominantly white fiber will respond better to lower repetitions and heavier weights. However, no one is any single somatotype, most of us are a combination of all three, so there is no canned program that will yield the best results. For overall size gains, the goal of a bodybuilder, using a multitude of rep ranges, poundage’s and varying intensity will be most beneficial as well as staying in your 55-85 percent maximum range. If your max on bench press were 200lbs, using varying weights of 110lbs up to 170lbs would be your “training zone”. That does not mean you should never go above or below those poundage’s, it just means that the majority of training you do should be within that range. Typically, for hypertrophy to take place your reps should be in the 4-8 range. There is no need to ever use a weight that you cannot perform at least 4 reps with, unless your goal is pure strength. There are a few reasons that I say this, one is that when you train at 90 percent or higher of your maximum weight Type IIb muscle fibers are doing the majority of the work, and this will not do much for hypertrophy. In fact, even power lifters and Olympic lifters do the majority of their training at around 85% of their max. You may be thinking that 55-85 percent is quite a difference in poundage, well it is. This is where periodization comes into play. Periodization is a concept where you use cycles to break up your training. Regardless of your ultimate goal you should have a plan, and this plan needs to be broken up into your daily, weekly, and monthly workouts. So, you may have a week of heavy intense training, then a maintenance week of lighter training, the light week allows the muscles to recuperate, yet because they’re still being trained atrophy will not occur from disuse. In order to avoid a state of over training, and continue to grow, we need to recover. Remember your muscles do not grow in the gym, they grow when at rest. Many factors contribute to over training, including inadequate rest, continued heavy training, and deficiencies in diet & nutrition. By using periodization to map out your training you will avoid over training and keep your muscles in a state of continued adaption. Principles that can be used when planning your training cycles: Cycle Training: this is where you break up your training into bulk cycles, strength cycles and cutting cycles; which will help keep your muscles in a responsive state. Split Training: this is breaking up your training into separate body parts each work-out which allows for shorter and more intense sessions. Muscle Confusion: your muscles adapt to stress, and ultimately you can reach a plateau. By constantly varying the exercises, weights, sets and reps you can ensure continued adaption. Progressive Overload: continue to increase different parameters in your training, whether it be more weight, increasing sets and reps, etc. Eclectic Training: using a variety of methods in your training, combining numerous techniques such as compound and isolation exercises. Principles that can assist you in arranging each workout: Supersets: alternating two opposing muscle groups with little rest in between sets. Giant Sets: performing several exercises for a single muscle group with little rest in between sets. Muscle Priority: training a weaker body part first in your work out. Pre-Exhaustion: this is where you perform an isolation exercise preceding a compound exercise, e.g. leg extensions before squats. Pyramiding: beginning with a lighter weight, gradually increasing weight and lowering reps, then work backwards, decreasing weight and increasing reps. Stripping: going from a heavy weight, and stripping off weight each set as fatigue sets in. Principles that can be used with each exercise: Forced reps: once failure has been reached on a set, your partner assists you in performing additional reps that could not be performed alone. Continuous tension: maintaining slow continuous tension thru out the rep, which will maximize red muscle fiber recruitment. Cheating: once failure is reached the weight is swung past your sticking point to complete the movement. (useful when you do not have a spotter) Partial reps: as the name implies only part of the full movement is performed, e.g. only curling a barbell half way up, which can be effective due to the varying points of leverage. Peak contraction: at the completion of a set holding the weight fully contracted for a few seconds. Super speed: using a lighter weight, reps are performed explosively yet controlled, called “compensatory acceleration”, which can help with white fiber recruitment. Another very important component of your training and growth is nutrition. Unfortunately, the scope of this article is not diet and nutrition, but I want to emphasize its importance. Since protein is required for anabolism, it’s crucial that your protein intake be adequate. The general rule of thumb for protein requirements is 1 to 1.5 grams of protein per pound of bodyweight. This means that a 200lb bodybuilder should be consuming 200-300 grams of protein per day spread across 5-6 meals each day (33 to 50 grams per meal). You should consume protein from a variety of sources, including red meat, chicken, eggs, milk, fish, cheese and whey to name a few. Many times people will say they just cannot gain weight; well the answer is simple “eat more calories”. In order to gain weight, including muscle mass, you must be consuming more calories than you’re burning, period. So, if you feel that you’re doing everything correctly in regards to training, and you’re not gaining weight, try increasing your calories by 200-300 per day. I am not saying the answer is that simple, although often times it is, I am just making the point that you cannot gain weight without adequate calories. For more detailed information on diet and nutrition please see the section on this site where you will find several articles on the subject.