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Being a natural athlete I’ve always sought to find more ways to increase testosterone levels naturally. The question I’ve always asked myself was what are the variables, which determine how much testosterone is boiavailable. I’ve read articles before, giving some advice on what in my every day life causes my test levels to go up and what causes them to go down. But after an extensive research I couldn’t find an article, explaining in detail how and actually what exactly I should manipulate directly in my system to achieve the effects I desired – namely not only higher levels of circulating testosterone but also how much of it will be available to the corresponding receptors in the cell walls. Moreover, I wanted to know all this in regards to natural bodybuilding… So, I decided to do some good digging and reading and then if I manage to put things together, to lay that in writing form so that others can benefit as well. Without wasting even a minute more I will start this off by describing what testosterone is and what it does in the human body. Testosterone is a steroid hormone with anabolic and androgenic properties. It is the main hormone, responsible for the increase in lean muscle tissue, increased libido, energy, bone formation, and immune function. Testosterone is secreted in the testes in men and in the ovaries in women. Small amounts are also secreted in the adrenal glands. Testosterone is derived from cholesterol. The levels of testosterone in men range between 350 and 1,000 nanograms per deciliter (ng/dl). After the age of 40 these normal levels start dropping by roughly 1 per cent a year. In the blood stream testosterone circulates in great percentage bound to so called binding proteins. Sex Hormone Binding Globulin or SHBG is the one that concerns us the greatest. Why? Because this is the main reason why testosterone might not be available to reach the cell receptor. When testosterone gets attached to SHBG, it is no longer able to perform its anabolic functions. What elevates SHGB: Anorexia nervosa, Hyperthyroidism, Hypogonadism (males), Androgen insensitivity/deficiency, Alcoholic hepatic cirrhosis (males), Primary biliary cirrhosis (females). What suppresses SHGB: Obesity, Hypothyroidism, Hirsutism (females), Acne vulgaris, Polycystic ovarian disease, Acromegaly, Androgen-secreting ovarian tumors Less than 1% of the circulating testosterone is in a free form in males (less that 3% in females). Only when in a free form this hormone can exhibit its properties by connecting to the androgen receptors on the cell walls. Based on a study 14 to 50 per cent of the testosterone is bound to SHBG in males and 37 to 75 in females. It is worth mentioning that SHGB poses very high affinity for binding to testosterone. Therefore, changes in the SHGB levels noticeably influence the level of bioavailable testosterone. Let’s discuss for a moment what exactly a testosterone bioavailability is. Other than SHGB there are two more testosterone-binding proteins, also called carriers. One of them is albumin. It is a low-affinity binding protein, thus testosterone bound to it is considered “bioavailable”. Albumin binds to testosterone in the range 45 to 85 per cent in men (25 – 65 in women). The third carrier is the cortisol binding globulin, which binds also with low-affinity to less that 1 % of the testosterone in circulation. The free androgen index (FAI) indicates the amount of bioavailable testosterone. FAI is the sum of the free testosterone and the albumin and cortisol binding globulin. Or it’s the total serum testosterone minus the SHGB-bound testosterone. It is now clear why we should focus our attention on the properties of SHGB. The levels of this binding protein increase when there is excess estrogen present. Conversely, SHGB levels drop if the testosterone levels are elevated. Here I should mention the fact that SHGB exhibits higher affinity to testosterone than to estrogen. Now, pay close attention… It’s a well-known fact that testosterone is an estrogen precursor – it will convert to estrogen under the influence of the enzyme aromatase. Nothing that we don’t know so far. Here is where it gets interesting. Suppose that we have normal testosterone levels and we don’t suffer from any of the health ailments, which influence the SHGB levels. That means that SHGB levels are normal, too. Bare with me now. If more of this testosterone is converted to estrogen due to abnormal aromatase levels, the SHGB I will increase as well. SHGB, being more readily bound to testosterone, will leave us with excess estrogen levels in the system, which in turn will stimulate increased production of the SHGB protein from the liver. This whole process ultimately amplifies estrogen levels. Estrogen readily binds to the androgen receptors in cells thus leaving less opportunity for the free testosterone. Even more important, estrogen is the messenger molecule that signals the brain to decrease testosterone production. Another thing of great importance is the fact that over 40 per cent of the SHGB protein circulates unbound in the blood stream in man (over 80 per cent in women), and albumin circulates unbound almost all of the time. Thus increase in the total testosterone levels does not produce any noticeable changes in the free testosterone levels unless there is a significant increase like the one seen after synthetic steroid hormone administration. Well, this whole story brings us to the conclusion that the main approach should be - to keep the testosterone bioavailability high. In this regard a natural athlete should strive to: · Prevent testosterone levels from getting low · Attempt to increase the total testosterone as a means of keeping the testosterone levels from plunging · Block the testosterone-binding effects of SHBG · Lower the levels of the enzyme aromatase - less testosterone conversion to estrogen 1. How to prevent testosterone levels from getting low? - Obesity. Based on the way the testosterone-estrogen mechanism works, increased levels of estrogen will ultimately decrease the circulating testosterone. Excess fat causes more estrogen production due to the fact that fat cells are those, which manufacture estrogen. So, the more fat cells, the more estrogen in the blood and the less testosterone. - Drug and alcohol abuse. Alcohol has the property to inhibit your ability to remove estrogen from the blood stream by acting as a central nervous system depressant and also by decreasing zinc levels. - Stress elevates corticosteroid levels in the blood steam, which causes the testosterone levels to decrease. - Medications. Some medications, including estrogen and progesterone, lower the lutenizing hormone (LH) levels. LH is the hormone, responsible for the steroid hormones production. - Diabetes. Studies suggest that there is a link between type 2 diabetes and lower testosterone levels. - Hypertension and high cholesterol levels. These both cause the arteries to harden, this way decreasing the blood flow to the sex hormone producing organs. That of course leads to low sex hormone levels. - Aging. Fact is after the age of 40 test levels drops by roughly one per cent per year. We can’t do too much about that. The clock keeps ticking for all of us. However, we can try to manipulate testosterone levels in any other possible way. - Low fat diet. Low fat consumption causes increase of the SHGB, which means one thing – less free testosterone. It is considered that monounsaturated fats play an important role in testosterone levels and bioavailability. - Overtraining can contribute to as much as 40 per cent drop in testosterone levels. That is why it’s important to notice early the signs of overtraining and give the body a week or two well-deserved rest. - Not enough sleep. If you are not getting enough sleep the body is not recuperating well, which causes less testosterone and more corticosteroids to be released. Just to mention corticosteroids like cortisol are in fact catabolic hormones meaning they use up muscle tissue to provide the brain and the heart with energy. - Vitamin C. It suppresses the release of the stress hormone cortisol. Cortisol decreases testosterone levels. So, ultimately less cortisol, more testosterone. 2. How to boost testosterone levels - Incorporate basic movements that involve several muscle groups in your training routine. Good ones are squats, dead lifts, and military presses. Basic (compound) exercises have been shown to play an important role in the testosterone levels. - The greatest workout related testosterone production occurs with the use of heavier weights and lower rep range. A study shows that the best is 85 per cent of your one-rep max. - Tribulus terestris is a natural supplement, which has been shown in some studies to have the ability to increase the leutenizing hormone (LH) levels. As we already mentioned above, one of the functions of LH is to stimulate testosterone production by the testes. 3. Block the testosterone-binding effects of SHBG - Nettle root as a highly concentrated extract has shown to be effective at binding to SHBG and therefore it permits more free testosterone to circulate the system. It also acts as a 5-alpha reductase inhibitor. This is the enzyme, responsible for the conversion of testosterone to dihydrotestosterone (DHT), a more potent form of the male sex hormone, which causes prostate enlargement and ultimately cancer. Methanolic extract of nettle can also cut down the SHBG levels, which is another form of elevating the free testosterone in the blood stream. - Pygeum (prunus africana) is another herb, known to block the testosterone-binding effects of SHBG. Nettle root and pygeum extracts also benefit the prostate gland as a preventive treatment for benign prostatic hyperplasia (BPH) both by blocking the 5-alpha reductase action. - Avena Sativa is an extract from the straw of oats. It has somewhat different properties. It works by freeing bound testosterone, which increases the free testosterone in circulation. 4. Lowering aromatize levels - Zinc. The mineral zinc inhibits the aromatase enzyme that converts testosterone into excess estrogen. The recommended dose for inhibiting aromatase is 80mg daily. However, be sure the combined zinc quantity of all the daily supplements you are taking does not go over this benchmark. - Chrysin is a bioflavonoid that has shown a potential as a natural aromatase inhibitor. Chrysin is poorly absorbed in the system. It is found that when taken along with piperine, chrysin exhibits a lot better absorption. Supplementation with chrysin and piperine together might bring good results in reducing aromatase levels. How does this all apply to the sport of natural bodybuilding Let’s assume you are an individual, who exercises regularly and who doesn’t consider taking exogenous steroid hormones. With other words you are a natural athlete or enthusiast, who desires to keep his natural testosterone levels in the range, favoring good health and lean muscle mass build up. Here is what you do: 1. If you are even slightly overweight consider staring immediately a diet and training routine, tailored toward fat loss and lean muscle retention. 2. Consider also dropping the alcohol intake to absolute minimum if you want your efforts in keeping test levels high to give results. 3. Begin mastering some types of self-control or even meditation. These will take care of the excess stress levels. 4. Take medications only if they are absolutely essential for your health and are prescribed by your doctor. Talk to your personal physician to find out if there are any natural remedies to replace your current medications and if he recommends such approach for your health issue. 5. Keep your blood pressure and the serum cholesterol in check. 6. Eat enough good fats in your diet. Good means monounsaturated and omega-3 and 6 polyunsaturated fats. 7. Don’t ever overtrain. Sleep enough to promote good recovery. Signs of overtraining are loss of appetite, tiredness and irritability, lack of motivation, impaired mental focus, prolonged recovery periods. 8. Start relying more heavily on basic exercise movements. Train in the low rep range most of the time. 5 – 8 reps will ensure that you’re using weights that will eventually stimulate elevated testosterone levels. 9. It will only do you good if you decide to try some or all of these natural supplements: chrysin - piperine blend, nettle root extract, pygeum, avena sativa extract, and tribulus terestris. Try to find them in your local health store. Follow the directions for best results. 10. And you shouldn’t even consider training without supplementing your diet with enough vitamin C (at least 1g a day) and zinc (15mg min.). Take vitamin C with your multivitamin formula after breakfast, and post-workout with your protein shake. Zinc should be present in your multivitamin blend but this is not enough. Take zinc with magnesium in the form of ZMA right before you go to bed on an empty stomach. References: Ron Geraci, Men's Health, December 25, 2000; 13 Ways to Naturally Boost Your Testosterone Levels LE Magazine January 2000; Replenish Testosterone Naturally Plant extracts favorably alter hormone metabolism and improve sexual desire in men Jennifer A. Kelly, Ph.D. and Leo Vankrieken, Eur. Eng. Diagnostic Products Corporation; Sex Hormone Binding Globulin and the Assessment of Androgen Status Cockatoo.com; Avena Sativa - are oats an aphrodisiac? Gabe Mirkin, M.D.; High Cholesterol Causes Low Testosterone Bodybuilding.com, Chrysin Info And Products - Block Estrogen, Increase Testosterone penis enargement surgery photo plastic surgery penile enlargement vigrx results easy enlargement free penile surgery way buy penis enlargment pills penis enlargment testimonials magna rx testimonials best enlargement exercise penis
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Modern medicine seems to be winning the war against infectious diseases and is good at repairing the body from trauma, these used to be the main causes of ill health and death in western societies. The major cause of ill health and death in the 21st century in the western world is now from degenerative diseases such as coronary artery disease, arthritis, osteoporosis, Alzheimer’s and cancer. Modern medicine is less effective against these degenerative diseases because it has a blinkered approach of using drugs to suppress the symptoms and does not to look at the bigger picture of why the disease has come about in the first place. Modern medicine uses drugs to stop a single step in the overall process leading to illness which is ineffectual and has a high risk of side effects. Many people are ill in hospitals from side effects caused by their drug therapy for their original illness, this is called iatrogenic illness. For example painkillers can cause ulcerations and gastrointestinal pain, anti-ulcer drugs can cause impotence and Viagra a treatment for impotence can cause structural damage to the penis. As illustrated with modern medicine you can start with one symptom and end up with a multitude of health problems. This is most evident with the therapies to treat cancer - chemotherapy, radiotherapy and surgery are all debilitating, painful and disfiguring treatments which use a multitude of drugs to combat side effects. This is a typical approach of modern medicine in that it practices crisis management; it waits until the diagnosis then bombards the patient with drugs. This is all too late as by the time the symptoms of degenerative disease appear, the damage has already been done and drugs cannot address this. Modern medicine does not look at the overall picture and asks itself why are people getting these diseases in the first place and how can we prevent them. Degenerative diseases are the result of a mechanism within the body being tipped off balance causing slow deterioration into disease. For example, coronary artery disease happens when the speed of fats being oxidized and deposited in the artery walls is quicker than which the body can remove them. These problems arise when the body’s natural defense mechanisms are undernourished or overloaded. Even a slight imbalance if unchecked will lead to major problems many years down the line. The self-destructive ways that many people now live, tip their body’s scales from self-repair to self-destruction. Nutritional therapy recognizes that the body can self-repair itself over a period of time by increasing vital micro-nutrients, exercising and restricting the intake of harmful substances such as tobacco smoke, sugar, salt and alcohol. It recognizes that prevention is better than cure. A lot of people who look and feel healthy are in fact ‘pre-ill’ due to their self-destructive lifestyles, which in time will lead to a degenerative illness such as cancer and coronary artery disease. Nutritional therapy addresses the pre-ill problem and rectifies it before it becomes clinical. Most people in the developed world are depleted in most micro-nutrients which will over years develop into ill health; drugs cannot rectify this only good micro-nutrient repletion plan can. The main reasons for why we are depleted in micro-nutrients are: We don’t eat enough resulting in less micro-nutrients being consumed. We eat too much process foods that are depleted in micro-nutrients. The soil that animals and plant are raised on is depleted in key minerals which are due to use of intensive farming. Bad habits such as smoking, sunbathing and heaving drinking all deplete the body of anti-oxidants. As we get older we become more depleted in micro-nutrients this is because older digestive systems are less efficient in absorbing them. No one person’s nutritional requirements are the same, for example a 60 year old who has been a heavy smoker all his/her life would be different from a teenager who likes to eat junk food. A Nutritional Therapist would analyze each individual nutritional status and then tailor make a dietary plan specifically for him/her.? Nutritional therapy aims at reaching optimum nutritional levels which research shows will protect the body against degenerative diseases. A healthy diet which is rich in vegetables, fruits, soy, oily fish combine with moderate exercise plus cutting out smoking and heavy drinking and adding a good supplement plan will keep the body healthy.? In Dr Paul Clayton’s book ‘Health Defence’ he illustrates the complex subject of nutritional defence by visualizing a nine piece jigsaw which once put together will form the bigger picture of a nutritional plan which will defend against degenerative diseases and promote good health.? This is a concise version of his nutritional jigsaw. To protect your cells against free radicals by consuming anti-oxidants such as Vitamin C, Vitamin D, the flavonoids Q10 and the mineral Selenium. To consume Carotenoids such as beta carotene, lutein and lycopene which have anti-oxidant and anti-cancer properties. To take Flavoniods such as grapeseed extract, green tea extract and pycnogenol which are strong anti-inflammatory and anti-aging agents, these will also protect against heart disease, cancer, asthma and arthritis. To consume Omega 3 oils which are found on oily fish and certain plants, these defend against conditions such as asthma and arthritis. 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1. WHAT ARE SEXUALLY TRANSMITTED DISEASES (STDS)? Sexually transmitted diseases are diseases that can be passed from person to person through sexual contact. In this case sexual contact means penis-vagina penetration, oral sex which is sexual contact using the mouth, and insertion of the penis into the rectum which is anal sex. Some of these diseases may be transmitted by exchange of sexual fluids such as semen or vaginal discharge. Some of the STD's result in open sores, and it can be spread by contact with skin of someone else. There are also ways to transmit these diseases in a non sexual way, an infected pregnant woman can either give it to her baby during pregnancy, or when the baby is being delivered. Drug abusers can transmit the disease through sharing hypodermic needles that have been used by an infected person. The seriousness of STD's varies, some are cured easily by drugs, others need a combination of treatments and drugs, whilst others have no cure, and the only option is treatment. 2. WHAT ARE SEXUALLY TRANSMITTED IINFECTIONS (STI's)? Any infection that is usually passed through sexual contact. 3. ARE THE TWO WORDS INTERCHANGEABLE? Fifteen years ago both these categories came under one name Venereal Disease (VD). To distinguish between them they were separated into infections (STI) and diseases(STD). Infection means that a germ, bacteria, parasite or virus is present in the body. An infected person does not necessarily have any symptoms, which means that they do not usually feel ill..A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress, in other words your body tells you that you are unwell. This means that STI covers a wider range than the term STD. STD refers only to infections that are causing problems. Because most of the time, people don't know they are infected with an STI until they start showing symptoms of disease, the AIDS Resource Center uses the term STD, even though the term STI is also appropriate in many cases. Let's see if we can simply un-muddy the waters here. Genital herpes has two states when the blisters are present and when they are absent. When they are present they are causing symptoms, ie the blisters, at this stage it is an STD, and it is that this stage that the infection is most likely to be spread to another person.When the blisters are absent then there are no symptoms, and this is then an STI, and the likelihood of an infection is reduced. However HIV can be an infection, in the sense that there may be no symptoms, when they develop symptoms then they have AIDS which is an STD. However it is important to remember that HIV infection can be spread at any time. 4.WHAT IS THE RELATIONSHIP BETWEEN STD'S AND HIV? A person who is already infected with STD, has a higher risk of contracting HIV if they have unprotected sex, without a condom. This risk is greater if the STD causes open genital sores, as these wounds provide a break in the skin which enables the HIV infection to enter the blood stream. STDs that can cause genital ulcers include genital herpes, syphilis, chancre, gonorrhoea, trichomoniasis, and scabies. 5.WHY IS IT DIFFICULT TO RECOGNIZE THAT YOU MAY HAVE A STD? First of all the majority of the people with STD have no immediate symptoms and when they do have them it can be misleading to diagnose as the symptoms can be confused with non sexual diseases. Please note that this applies much more to women than men. 6. WHAT ARE THE MOST COMMON SYMPTOMS FOR WOMEN WHEN THEY ARE SUFFERING FROM AN STD? unusual or bad-smelling vaginal discharge, severe itching or burning in the genital area, unusual bleeding, pain in the pelvic region, pain during sex, rashes on the genitals, open sores or warts on the genital area, and/or recurrent urinary tract infections. 7. WHAT ARE THE MOST COMMON SYMPTOMS FOR MEN WHEN THEY ARE SUFFERING FROM AN STD? In men, the most common symptoms of STD are: pain when urinating, open sores or warts on the genital are genital rash discharge from the penis, and/or pain in the scrotum/testicles. 8. WHAT ARE THE OTHER SYMPTOMS NOT CONNECTED TO THE GENITALS? The following symptoms are present in both men and women: discharge from the anus, swelling of the groin, jaundice (yellowing of the skin and whites of the eyes), oral thrush (white tongue), arthritis, sores or bumps in and around the mouth, and generalized rashes. 9 CAN I CONTRACT STI AS A RESULT OF MUTUAL MASTERBATION? Yes you can and listed below are some examples: Bacterial Vaginosis Cytomegalovirus (CMV) Herpes Simplex Human Papilloma Virus (HPV, Warts) Pubic Lice Scabies 10. CAN I PREVENT GETTING STI or STD? The only foolproof way is abstinence from sex. A condom merely reduces the risk, and it must be used every time, before any sexual fluids are exchanged. pennis enlargement doctor best penis elargement pnis enlargement fact magna rx pill penis enlargement surgeon penis enhancement surgeon penis enhancement pump cheap pnis enlargement natural penile enlargment pills
VIAGRA What is Viagra? Viagra is an anti-impotence drug manufactured by Pfizer with an active ingredient sildenafile citrate for treatment of male impotence. Sildenafile citrate relaxes the muscles and increases the blood flow to particular areas of the body. The intake of Viagra increases the ability to achieve and sustain erection on being sexually stimulated. Men taking Viagra have reported an amplified sex drive, increased stamina, and quicker recharge. Viagra works together with sexual stimulation to help achieve maximum sexual satisfaction. However, Viagra does not guarantee protection from getting sexually transmitted diseases, including HIV and Hepatitis. How Viagra works? Viagra enables many men with ED to respond to sexual stimulation. When a man is sexually aroused, the arteries in the penis relax and widen, allowing more blood to flow into the penis. As the arteries in the penis expand and harden, the veins that normally carry blood away from the penis become compressed, restricting the blood flow out of the penis. With more blood flowing in and less flowing out, the penis enlarges, resulting in an erection. It is to be noted that Viagra is not a hormone or aphrodisiac, it works only when a man is sexually stimulated. Viagra Dosage Viagra is available in the form of tablet and is meant to be taken orally. Ideally it is to be taken almost an hour before the sexual activity. However, Viagra can be taken anytime from 4 hours to 30 minutes before sexual activity. It takes 30 – 45 minutes for showing Viagra’s effect and this effect lasts for almost four hours. If you take Viagra after a high-fat meal (such as fish & chips, cheeseburger or French fries), it may take a little longer to start working. Viagra should not be taken more than once a day unless prescribed by your doctor. Warnings/Precautions It is always advisable to consult physician before starting the intake of Viagra. In case you have the history of an heart attack, stroke, or life-threatening irregular heartbeats within the last six months; or have heart failure in the past; coronary artery disease; angina; high or low blood pressure; liver problems; kidney problems; blood problems, including sickle cell anemia or leukemia; a bleeding disorder; stomach ulcer; retinitis pigmentosa (an inherited condition of the eye); physical deformity of the penis such as Peyronie's disease; or a condition that could lead to prolonged and painful erections, such as a tumor of the bone marrow, sickle cell anemia, or leukemia; or you are taking any other medicine containing nitrates your blood pressure could suddenly drop to an unsafe level and can risk your life. All these medical conditions and also allergy to sildenafile or any of its ingredients can lead to disastrous results. So it is always advisable to consult your doctor for adjusting the dosages after monitoring the treatments listed above. Viagra is not approved or recommended for use in women. Therefore, women should not take Viagra under any circumstances. It also not recommended for men older than 65 years unless they tolerate it in small doses for those who are sensitive to the effects of Viagra. Missed Dose Viagra can be taken as and when needed and there is no concept of missed dosage. Possible Side Effects of Viagra Every medicine has some or the other side effect and so does Viagra. It depends on individual to individual and is usually mild to moderate and don't last longer than a few hours. Mostly these side effects are evident with high intakes of Viagra. The most common side effects of Viagra are headache, nausea, flushing of the face, and upset stomach. Also there can be some temporary changes in color vision (such as trouble telling the difference between blue and green objects or having a blue color tinge to them), eyes becoming sensitive to light, or blurred vision. But if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw during sexual activity, stop and call your doctor right away. You could be having a serious side effect of Viagra, or if you have sudden vision loss or have any of these signs of allergic reactions like hives; difficulty breathing; swelling of your face, lips, tongue, or throat seek emergency medical help immediately. It is also advisable to stop using Viagra and call your doctor immediately if you have any of these serious problems like - chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; irregular heartbeat; swelling in your hands, ankles, or feet; shortness of breath and vision changes. In rare instances, men have reported an erection that lasts many hours. But if this is the case then you should call a doctor immediately if an erection lasts more than 4 hours. If not treated right away, permanent damage to your penis could occur. Heart attack, stroke, irregular heartbeats, and death have been reported rarely in men taking Viagra. Most, but not all, of these men had heart problems before taking this medicine. It is not possible to determine whether these events were directly related to Viagra.